Sumatriptāns ir zāles, ko lieto migrēnas un klastera galvassāpju ārstēšanai. 3D ilustrācija

Vai triptāni ir piemēroti migrēnas galvassāpju ārstēšanai?

Daudziem miljoniem cilvēku, kas cieš no migrēnas, ir bijis grūti atrast efektīvu līdzekli, un tam ir bijis nepieciešams ievērojams laiks. . Even after years of study there’s absolutely no miracle , but a new class of drugs called triptans are as close to a miracle cure as we’ve come for these often intensely painful headaches that could strike at any moment.

Triptāni

Triptāni ir sava veida zāles, kas ķīmiski ir līdzīgas serotonīnam, kas pats par sevi ir serotonīna. that’s thought to play a role in causing migraines. Like many drug treatments, success often comes from developing a compound that’s chemically similar to a naturally occurring compound in the un to izmantot, lai palielinātu līmeni organismā, kad rodas simptomi. Šajā gadījumā triptāni piestiprinās pie receptoriem, kuros parasti tiek atklāti organisma dabiskie bioķīmiskie, bet uzvedība nedaudz atšķiras, lai mazinātu simptomus.

Technically triptans are in a class of drugs called 5-HT1B/1D agonists. Although these new medications have been proven to be effective in many cases of there are some studies that suggest they are more effective for migraine sufferers who lack . For those men and women who do lēkmes laikā triptānus var lietot arī turpmāk, taču tie jālieto pēc iespējas ātrāk pēc migrēnas parādīšanās un vēlams ne vēlāk kā 20 minūtes pēc simptomu parādīšanās. Bieži vien migrēnas slimniekiem pirms lēkmes sākuma rodas tā sauktā "aura". un tas ir ne tikai brīdinājuma signāls, ka tuvojas galvassāpes, bet arī signāls, lai sāktu ārstēšanu.

Labi zināt

Although not all victims will experience a feeling for the ones that do it varies widely but is basically a visual disturbance consisting of such things as viewing spots or flashing lights. Triptan drugs were first introduced during the 1990s and there are now various diverse kinds of these drugs available under an assortment of different commercial names.

One quite common treatment is sumatriptan, which is sold under the brand name of Imitrex. This first generation of medication proved very powerful but still didn’t quite do the trick in addition to physicians would have desired and so now we see another generation of more effective triptans. These include (marketed as Zomig) and (marketed as Maxalt). These next generation drugs are often known as ‘aborters’ or ‘interrupters’ since they are intended to prevent a migraine in its early stages and until it builds into the intense and pulsating that’s so familiar to migraine sufferers.

Second generation triptans are favored by many victims because they don’t need to be obtained before the coming of the headache, which can be tricky to predict as symptoms aren’t always very pronounced. Additionally, they are effective for a longer time period, which is also essential for those people whose migraines can last for days as opposed to hours. Triptans can also help relieve or remove other migraine symptoms like nausea and .

Secinājums

Vēl viena problēma, kas ir bieži klāt ar parastajiem medikamentiem, kas veikti tablešu veidā, ir tie prasa, lai jums ir ūdens pa rokai, lai ņemtu tableti un veikt laiku, lai darbotos, jo tabletes ir sadalīti un uzsūcas uz . Tomēr daudzus no jaunajiem triptāniem, piemēram, rizatriptānu (reklamē kā Maxalt), var atrast vafeļu formā, kas izšķīst tikai uz... tagad ir pieejami deguna aerosoli, kas ļoti ātri iedarbojas.