Candida species are extremely common and in order Candidiasis. The truth is there are more than one hundred species of Candida which are present almost anywhere. The most clinically important one of the Candida fungi is Candida albicans. This fungus causes the majority of the disease among human beings. The Candida fungi are found in the skin of approximately 80 percent of all human beings.
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About 30% to 50% young people in good health are believed to possess the fungi from the oropharynx, part of the pharynx between the soft palate and the epiglottis, while 3 out of 4 girls can have vaginal candidiasis. Infection on the skin is easily treated with antifungal cream or lotions. Most of these topical antifungal medications can be purchased over-the-counter. However, some need to experience oral medication that’s only available with the doctor’s prescription.
People with recurrent Candidal infection are usually immunocompromised individuals. These individuals have weak immune system because of underlying disorders or critical health conditions. Immunodepressed people are also prone to acute infection; these folks use drugs to control immune reaction. In such individuals, the disease becomes systemic, meaning blood is already infected by the Candida fungus.
It usually affects quite vital organs of the body like the heart, the lungs, the liver and the kidney. Symptoms of this include high fever, urinary tract infection, blood in the urine anemia, difficulty in breathing, blood in the sputum, allergies and septic shock. There are two kinds of systemic canidiasis: candidemia, the presence of the fungi in the blood and disseminated candidiasis, the fungal disease of the inner organs.
Candidemia is deemed nosocomial infection, meaning it takes place when the patient is already admitted to a hospital. It happens within 72-hour period after the individual has been admitted. Before the entrance into the hospital, the patient undergoes fever which can’t be treated by any antifungal medication, skin lesions and intermittent septic shock;’d organ infections (due to other factors), had used prosthetic valves; also has been catheterized for a lengthy time period.
Disseminated systemic candidiasis is associated with deep infections of many organs in the body. Although patients with disseminated candidiasis usually have poisonous germs in the bloodstream and encounter septic shock and fever not responsive to medication, doctors find it tough to detect disseminated candidiasis. This is because blood tests of 40% to 60% of these show there aren’t any Candida fungi in the blood. The sufferers are only presumed to have candidiasis based on their own history.
Any kind of candidiasis becomes harmful to the individual’s life when it becomes invasive that is, the Candida fungi infect many organs and tissues within the body. Invasive Candidal infection can lead to multiple organ failure and even death. Patients with Candidemia and Dissimilated Candidiasis are often given with Fluconazole medication as treatment. This medication can be taken orally, can be administered intravenously or vaginally. Fluconazole drugs are easier to use and have more life. They also have lower nephrotoxicity speed (less than two percent). Nephrotoxicity is the poisonous effects of the medication to the kidney. However, this sort of drug is also thought to have high hepatotoxicity prices. Hepatotoxicity denotes the medication’s intoxicating effects to the liver.